Home Blog Thermal Shift Assay for Inhibitors of 15-Hydroxyprostaglandin Dehydrogenase
Thermal Shift Assay for Inhibitors of 15-Hydroxyprostaglandin Dehydrogenase PDF Print
Written by Sarkis Dallakian   

Here are the results of a new PubChem BioAssay AID: 2427 with 42 compounds (22 active, 2 inactive and 18 inconclusive).

AutoDock did a perfect job here giving favourable binding energy for active compounds compared to inactives. As a result, we have a prefect ROC curve here. I made the makers bigger so you can see that all actives are on a vertical x=0 line and all inactives lay on a horizontal y=1 line.


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Last Updated on Thursday, 29 September 2011 09:32
 
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